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Published on: August 22, 2016
Acellular dermis for facial soft tissue augmentation: preliminary report
P D Costantino1, S Govindaraj, D H Hiltzik
1Department of Otolaryngology, Box 1189, The Mount Sinai Medical Center, 1 Gustave L. Levy Pl, New York, NY 10029, USA.
Objective:
To evaluate the efficacy of acellular dermis as a viable alternative for soft tissue augmentation in facial reconstruction.
Design:
A prospective, nonrandomized observational study consisting of 10 patients who underwent soft tissue augmentation with acellular dermis.
Setting:
A tertiary care university medical center in an urban setting.
Patients:
Ten patients who had undergone soft tissue augmentation using acellular dermis participated in this study. Postimplantation follow-up was 17 to 36 months.
Intervention:
The amount and location for placement of the acellular dermis was left to the discretion of the surgeon. All implants were placed in the subdermal tissues.
Main Outcome Measures:
The adequacy of acellular dermis for soft tissue augmentation was assessed by subjective evaluation of implant volume persistence, postoperative complications, and the restoration of normal contour.
Results:
Of 10 patients who underwent implantation, 9 had no complications and 1 had a recurrent sterile abscess or mucocele at the implantation site. A 22-month postimplantation tissue sampling of acellular dermis in a patient with recurrent tumor revealed approximately 80% to 85% volume persistence.
Conclusion:
Preliminary experience with acellular dermis indicates that it shows promise in soft tissue augmentation.
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