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Acellular dermis for facial soft tissue augmentation: preliminary report.
P D Costantino1, S Govindaraj, D H Hiltzik
1Department of Otolaryngology, Box 1189, The Mount Sinai Medical Center, 1 Gustave L. Levy Pl, New York, NY 10029, USA.
Archives of Facial Plastic Surgery
|February 15, 2001
Summary
Acellular dermis shows promise for soft tissue augmentation in facial reconstruction, with 90% of patients experiencing no complications. This material demonstrated significant volume persistence over time.
Area of Science:
- Regenerative medicine
- Plastic surgery
- Biomaterials science
Background:
- Facial reconstruction often requires soft tissue augmentation.
- Acellular dermis is being explored as a potential biomaterial for these procedures.
Observation:
- A prospective observational study evaluated 10 patients undergoing facial soft tissue augmentation with acellular dermis.
- Implants were placed subdermally, with follow-up ranging from 17 to 36 months.
Findings:
- Acellular dermis demonstrated good efficacy, with 90% of patients experiencing no complications.
- One patient developed a sterile abscess. Tissue sampling indicated 80-85% volume persistence at 22 months.
Implications:
- Acellular dermis presents a promising alternative for soft tissue augmentation in facial reconstruction.
- Further research is warranted to confirm long-term efficacy and safety.