Related Experiment Video
Updated: Oct 2, 2026
06:08
Apical Resection Mouse Model to Study Early Mammalian Heart Regeneration
Published on: January 23, 2016
Death, elimination, and regeneration of cardiomyocytes in mice after hyperthermia
E L Lushnikova1, L M Nepomnyashchikh, O P Molodykh
1Laboratory of Cytology and Cell Biology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Bulletin of Experimental Biology and Medicine
|February 15, 2001
Abstract:
Single total hyperthermia changed the absolute number of cardiomyocytes in experimental animals. The total number of cardiomyocytes decreased by 20% (without signs of their necrosis) on day 3 of post-heating restitution and then returned to the control. This was probably related to cytokinesis (without karyokinesis) of binucleated cells, whose content considerably decreased during recovery.
