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Sarcoidosis with vocal fold involvement and hypercalcaemia.

S Matsumoto1, M Nakahira, H Nakatani

  • 1Departments of Otolaryngology, Kochi Medical School, Kochi, Japan.

The Journal of Laryngology and Otology
|February 15, 2001
PubMed
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Laryngeal sarcoidosis is rare, often affecting the supraglottis. This case highlights unusual vocal fold involvement in sarcoidosis, emphasizing its consideration in vocal fold lesions, especially with hypercalcemia.

Area of Science:

  • Otorhinolaryngology
  • Pulmonology
  • Endocrinology

Background:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Laryngeal involvement is uncommon, typically affecting the supraglottis.
  • Vocal fold involvement is rarely detailed.

Observation:

  • A 66-year-old man presented with laryngeal sarcoidosis primarily affecting the vocal folds.
  • The case was associated with hypercalcemia, a known feature of sarcoidosis.
  • Detailed characteristics of vocal fold involvement were observed.

Findings:

  • This report presents an unusual case of laryngeal sarcoidosis with initial vocal fold presentation.
  • Hypercalcemia was a significant associated clinical feature.
  • The vocal folds exhibited distinct characteristics due to sarcoidosis.

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Implications:

  • Laryngeal sarcoidosis should be considered in the differential diagnosis of vocal fold lesions.
  • The presence of hypercalcemia increases suspicion for sarcoidosis in vocal fold pathology.
  • Further research may elucidate the specific mechanisms and presentation of vocal fold sarcoidosis.