Sarcoidosis with vocal fold involvement and hypercalcaemia

Area of Science:

• Otorhinolaryngology
• Pulmonology
• Endocrinology

Background:

• Sarcoidosis is a multisystem inflammatory disease.
• Laryngeal involvement is uncommon, typically affecting the supraglottis.
• Vocal fold involvement is rarely detailed.

Observation:

• A 66-year-old man presented with laryngeal sarcoidosis primarily affecting the vocal folds.
• The case was associated with hypercalcemia, a known feature of sarcoidosis.
• Detailed characteristics of vocal fold involvement were observed.

Findings:

• This report presents an unusual case of laryngeal sarcoidosis with initial vocal fold presentation.
• Hypercalcemia was a significant associated clinical feature.
• The vocal folds exhibited distinct characteristics due to sarcoidosis.

Implications:

• Laryngeal sarcoidosis should be considered in the differential diagnosis of vocal fold lesions.
• The presence of hypercalcemia increases suspicion for sarcoidosis in vocal fold pathology.
• Further research may elucidate the specific mechanisms and presentation of vocal fold sarcoidosis.