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Enhanced External Counterpulsation in Unrevascularizable Patients.

Gregory W. Barsness¹

¹Mayo Clinic and Foundation, 200 First Street, SW, Rochester, MN 55905, USA. barsness.gregory@mayo.edu

Current Interventional Cardiology Reports

|February 15, 2001

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Enhanced external counterpulsation (EECP) offers a noninvasive therapy for chronic angina, improving cardiac output and providing symptom relief. This outpatient treatment demonstrates significant clinical response rates in patients with ischemic heart disease.

Area of Science:

Cardiology
Noninvasive Cardiovascular Therapies

Background:

Chronic angina impacts quality of life and necessitates effective treatments.
Existing therapies may be invasive or have limitations.
Noninvasive options are sought for managing ischemic heart disease symptoms.

Purpose of the Study:

To summarize the efficacy and application of Enhanced External Counterpulsation (EECP) for chronic angina.
To describe the hemodynamic effects and clinical outcomes of EECP therapy.
To outline the treatment protocol and safety profile of EECP.

Main Methods:

EECP involves sequential inflation/deflation of leg cuffs during the cardiac cycle.
Treatment consists of 35 one-hour sessions over seven weeks.
Patient selection and response assessment are key components.

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Main Results:

EECP mimics intra-aortic balloon pump hemodynamic effects.
Therapy increases diastolic aortic pressure and coronary perfusion.
Up to 80% of selected patients show positive clinical response with objective improvements.
The treatment is generally well-tolerated with low adverse event risk.

Conclusions:

EECP is a safe and effective noninvasive outpatient therapy for chronic angina.
It provides long-term symptom relief and objective functional improvement.
Mechanisms may involve collateral channel development and neurohumoral effects.