Related Experiment Videos
Force dependence of the Michaelis constant in a two-state ratchet model for molecular motors
1International School of Advanced Studies and Istituto Nazionale di Fisica della Materia, trieste, Italy.
Physical Review Letters
|February 15, 2001
Abstract:
We present a quantitative analysis of recent data on the kinetics of ATP hydrolysis, which has presented a puzzle regarding the load dependence of the Michaelis constant. Within the framework of coarse grained two-state ratchet models, our analysis not only explains the puzzling data, but provides a modified Michaelis law, which could be useful as a guide for future experiments.