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Updated: Jul 16, 2026

RNAi Interference by dsRNA Injection into Drosophila Embryos
Published on: April 11, 2011
Multiple RNA-protein interactions in Drosophila dosage compensation
1Department of Genetics, Duke University Medical Center, Research Drive, Durham, NC 27710, USA. hoa1@duke.edu
Abstract:
From worms to humans, recognizing and modifying a specific chromosome is essential for dosage compensation, the mechanism by which equal X-linked gene expression in males and females is achieved. Recent molecular genetic and biochemical studies have provided new insights into how regulatory factors in Drosophila are recruited and assembled on the X chromosome, leading to the essential hypertranscription of its genes.
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