Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Direct strain estimation in elastography using spectral cross-correlation.

T Varghese1, E E Konofagou, J Ophir

  • 1Ultrasonics Laboratory, The University of Texas Medical School, Houston, TX, USA. tvarghese@facstaff.wisc.edu

Ultrasound in Medicine & Biology
|February 17, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.

Scientific reports·2023
Same author

Long term study of motivational and cognitive effects of low-intensity focused ultrasound neuromodulation in the dorsal striatum of nonhuman primates.

Brain stimulation·2022
Same author

Early Detection of Acute Kidney Injury by Neutrophil Gelatinase Associated Lipocalin in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass.

Mymensingh medical journal : MMJ·2021
Same author

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.

Molecular and cellular neurosciences·2020
Same author

<i>In vivo</i> carotid strain imaging using principal strains in longitudinal view.

Biomedical physics & engineering express·2019
Same author

A Cross-Sectional Investigation of Cognition and Ultrasound-Based Vascular Strain Indices.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2019
Same journal

Region-Specific Evaluation of Plaque Segmentation in Cross-sectional Projections of Carotid Ultrasound Images Using Deep Learning Models in a Sub-clinical Atherosclerosis Cohort.

Ultrasound in medicine & biology·2026
Same journal

Simulating the Dedifferentiation Process of Thyroid Cancer: Insights from Mouse Models and Ultrasound Imaging.

Ultrasound in medicine & biology·2026
Same journal

A Nomogram Based on Ultrasound Features for Predicting Major Intra-Operative Hemorrhage in Patients With Placenta Accreta Spectrum (PAS).

Ultrasound in medicine & biology·2026
Same journal

MedLP-HAFB-CLIP: Hierarchical Adaptive Large Model With Learnable Medical Prompts for Level II Ultrasound Standard Plane Identification.

Ultrasound in medicine & biology·2026
Same journal

Data Assimilating B-splines for Model-based Regularization in Ultrasound Vector Flow Imaging.

Ultrasound in medicine & biology·2026
Same journal

Low-Intensity Focused Ultrasound Enhances Hippocampal Neurogenesis via BDNF Pathways: Toward a Regenerative Modality for CNS Recovery.

Ultrasound in medicine & biology·2026
See all related articles

This study introduces spectral cross-correlation for more accurate tissue strain estimation. This new method improves sensitivity for detecting small strains compared to the traditional centroid shift technique.

Area of Science:

  • Medical imaging
  • Ultrasound technology
  • Biomedical engineering

Background:

  • Tissue strain estimation is crucial for diagnosing various medical conditions.
  • Previous methods like centroid shift offer some accuracy but have limitations with small strains.
  • Accurate strain measurement is vital for effective medical diagnosis and treatment planning.

Purpose of the Study:

  • To introduce and evaluate a novel spectral cross-correlation method for tissue strain estimation.
  • To compare the performance of spectral cross-correlation against the established centroid shift method.
  • To demonstrate the enhanced sensitivity and precision of spectral cross-correlation for small strain detection.

Main Methods:

  • Utilized spectral cross-correlation of pre- and postcompression power spectra for strain estimation.

Related Experiment Videos

  • Compared spectral cross-correlation with the spectral centroid shift method.
  • Analyzed variance and noise properties using strain filters for both methods.

    • Main Results:

    • Spectral cross-correlation demonstrated higher sensitivity to small shifts in the power spectrum.
    • The new method provides more accurate and precise strain estimation for smaller strains.
    • Spectral cross-correlation retains the advantages of the centroid shift method while improving performance.

    Conclusions:

    • Spectral cross-correlation is a superior method for estimating tissue strain, especially for small strains.
    • This technique offers improved accuracy and precision in ultrasound-based strain imaging.
    • The findings suggest a significant advancement in quantitative ultrasound elastography.