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Related Experiment Videos

Serum triiodothyronine concentration in thyroid storm.

M H Brooks, S S Waldstein, D Bronsky

    The Journal of Clinical Endocrinology and Metabolism
    |February 1, 1975
    PubMed
    Summary

    Thyroid storm patients showed elevated serum triiodothyronine (T3) levels, similar to uncomplicated thyrotoxicosis. This indicates thyroid storm

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    Area of Science:

    • Endocrinology
    • Thyroid Disorders

    Background:

    • Thyroid storm is a severe manifestation of thyrotoxicosis.
    • The role of serum triiodothyronine (T3) levels in thyroid storm pathogenesis is debated.

    Purpose of the Study:

    • To compare serum triiodothyronine (T3) levels in patients with thyroid storm versus uncomplicated thyrotoxicosis.
    • To investigate the relationship between T3 concentration and thyroid storm severity.

    Main Methods:

    • Measurement of serum triiodothyronine (T3) levels in patients diagnosed with thyroid storm.
    • Comparison of T3 levels with those from patients with uncomplicated thyrotoxicosis.

    Main Results:

    • Serum triiodothyronine (T3) levels were elevated in patients with thyroid storm (769 ± 181 ng/100 ml).
    • Observed T3 levels in thyroid storm were not significantly different from those in uncomplicated thyrotoxicosis (752 ± 282 ng/100 ml).

    Conclusions:

    • The pathogenesis of thyroid storm likely involves mechanisms beyond a simple increase in serum triiodothyronine (T3) concentration.
    • Further research is needed to elucidate the complex pathophysiology of thyroid storm.

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