Related Experiment Video
Updated: Aug 5, 2026

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy
Published on: July 9, 2016
Functional, structural, and genetic mitochondrial abnormalities in myocardial diseases
A Brega1, J Narula, E Arbustini
1Department of Biology and Genetics for Medical Sciences, University of Milan, Italy.
Abstract:
Myocardial tissue is highly dependent on energy supplied by normal mitochondrial function. Therefore defects of energy production or utilization affect the heart in both syndromic and isolated disorders. Knowledge of the peculiar structural, functional, and genetic characteristics of mitochondria provides the basis for identification and classification of mitochondrial defects as well as for establishment of a diagnostic workup useful for related cardiac disorders. This review is therefore dedicated to the characteristics of normal mitochondria and the pathologic alterations of these organelles in various cardiovascular diseases.
Related Concept Videos
Mitochondrial Membranes
The Inner Mitochondrial Membrane
ATP Synthase: Mechanism
Structure of Cardiac Muscles
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
Myocarditis I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy

