[Microcirculation bed in chronic uremia]

Microcirculation of the bulbar conjunctiva and nailbed was studied in 120 patients with chronic renal failure (CRF) and its complications. Peritoneal, pleural and pericardial circulation was investigated in 15 dogs with experimental chronic uremia. It was found that the degree and frequency of microcirculatory disorders in chronic uremia correlate with the stage of CRF and diseases causing CRF. The presence of cardiac insufficiency aggravated CRF. Clinical, morphological, light and electron microscopic examinations of microcirculation in CRF revealed alterations in all the regions of microcirculation. Additional data on etiopathogenesis of cardiovascular disorders in CRF were obtained basing on the changes in peritoneal, pleural and pericardial microvessels in the experimental model of chronic uremia.