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Idiotypic regulation of anti-factor VIII antibodies
M D Kazatchkine1, S Lacroix-Desmazes, A Moreau
1INSERM U430 and University Pierre et Marie Curie, H pital Broussais, Paris, France.
Haematologica
|February 24, 2001
Abstract:
This review focuses on the relationship between natural autoreactivity, autoimmunity in disease and antigen-driven immune responses to factor VIII and on idiotype-mediated immune regulation of anti-factor VIII antibodies in health and disease.