[Medullary carcinoma of the stomach]

The aim of this work is to show the important histiocytic oblation present in a case of stomach medullary carcinoma, marked with silver technique of Del Río Hortega. This carcinoma is poor differentiated with a predominant lymphoid infiltrate, of better prognosis, that shares many characteristic with medullary carcinoma of breast, lung, nasopharynx, thymus and salivary gland. Histologic techniques: Hematoxilin & Eosin, PAS, PAS-Alcian blue, Alcian blue, Masson's trichrome, macrophagues Del Río Hortega-Polak, and reticulin Del Rio Hortega silver impregnations techniques. Gastric medullary carcinoma shows an important lymphoid infiltration T and B, and dendritic, plasmodials and giant multinucleated macrophagues in close relations with neoplasic cells. The results suggest that Epstein-Barr virus (EBV) becomes associated with gastric medullary carcinoma.