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[Hypertension and pulse pressure].

M Safar1, J Blacher, G London

  • 1Service de médecine interne 1, centre hospitalier Broussais-Georges-Pompidou, 96, rue Didot, 75015 Paris.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|February 24, 2001
PubMed
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Pulse pressure is a significant cardiovascular risk factor, particularly for myocardial infarction. Elevated pulse pressure poses risks even in treated hypertension, leading to isolated systolic hypertension.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Cardiovascular Risk Assessment

Context:

  • Pulse pressure is an established independent cardiovascular risk factor.
  • Its predictive value extends beyond general hypertension to specific conditions like congestive heart failure and myocardial dysfunction.
  • Isolated systolic hypertension is a concern, even in treated hypertensive patients.

Purpose:

  • To highlight the independent cardiovascular risk associated with pulse pressure.
  • To emphasize the predictive value of pulse pressure across various cardiovascular conditions.
  • To underscore the risk of isolated systolic hypertension in treated hypertensive individuals.

Summary:

  • Pulse pressure independently predicts cardiovascular events, notably myocardial infarction.

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  • This predictive power is evident in hypertensive individuals over 50, and patients with heart failure, myocardial dysfunction, or recurrent myocardial infarction.
  • Treated hypertensive patients remain at risk due to persistent elevated systolic blood pressure, a condition known as isolated systolic hypertension.

    • Impact:

    • Increased awareness of pulse pressure as a critical cardiovascular risk indicator.
    • Improved risk stratification for patients with various cardiovascular diseases.
    • Potential for enhanced antihypertensive treatment strategies to address isolated systolic hypertension.