Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antimicrobial therapy in the elderly.

S Rajagopalan1, T T Yoshikawa

  • 1Department of Internal Medicine, Division of Infectious Disease, Charles R. Drew University of Medicine and Science, King-Drew Medical Center, Los Angeles, California, USA. shrajago@cdrewu.edu

The Medical Clinics of North America
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integration of genomic aberrations to predict clinical outcomes for patients with gastroesophageal adenocarcinoma receiving neoadjuvant chemotherapy.

ESMO gastrointestinal oncology·2026
Same author

Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

Physical review letters·2026
Same author

Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

Physical review letters·2025
Same author

Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

Final overall survival and safety analyses of the phase III PSMAfore trial of [<sup>177</sup>Lu]Lu-PSMA-617 versus change of androgen receptor pathway inhibitor in taxane-naive patients with metastatic castration-resistant prostate cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2025
Same author

Observation of tt[over ¯] Production in Pb+Pb Collisions at sqrt[s_{NN}]=5.02  TeV with the ATLAS Detector.

Physical review letters·2025
Same journal

Care Transitions Continue to Evolve.

The Medical clinics of North America·2026
Same journal

Navigating the Gaps: A Comprehensive Overview of Care Transitions Across the Continuum.

The Medical clinics of North America·2026
Same journal

Care Transitions and Value-Based Payment Models in the United States.

The Medical clinics of North America·2026
Same journal

Technology and Innovation in Care Transitions: Imagining the Future of Postdischarge Care.

The Medical clinics of North America·2026
Same journal

Primary Care, Specialists, and Hospitals: Bridging the Gaps in Communication and Coordination.

The Medical clinics of North America·2026
Same journal

Social Determinants of Health: Unique Considerations in Transitions of Care.

The Medical clinics of North America·2026
See all related articles

This review updates antibiotic selection and use for infections in elderly patients, a vulnerable population. It covers empiric antimicrobial therapy principles for common infections in older adults.

Area of Science:

  • Geriatrics
  • Infectious Diseases
  • Pharmacology

Background:

  • Elderly individuals are a vulnerable population susceptible to infections.
  • Infections in the elderly present unique challenges in diagnosis and treatment.
  • Age-related physiological changes impact antimicrobial efficacy and safety.

Purpose of the Study:

  • To provide an update on managing infections in the elderly.
  • To review principles of antibiotic selection and use in older adults.
  • To discuss empiric antimicrobial therapy for common infections in this demographic.

Main Methods:

  • Literature review focusing on antimicrobial therapy in the elderly.
  • Synthesis of current guidelines and evidence for antibiotic use.

Related Experiment Videos

  • Discussion of specific antibiotic classes and their application in geriatric patients.

    • Main Results:

    • Antibiotic selection requires careful consideration of pharmacokinetic and pharmacodynamic changes in the elderly.
    • Empiric antimicrobial therapy should be guided by local resistance patterns and patient-specific factors.
    • Specific antibiotic choices and dosing adjustments are crucial for optimizing outcomes and minimizing adverse events.

    Conclusions:

    • Effective management of infections in the elderly necessitates a tailored approach to antimicrobial therapy.
    • Understanding age-related differences is key to successful treatment and improved patient outcomes.
    • Further research into geriatric infectious diseases and antimicrobial stewardship is warranted.