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Related Experiment Videos

[Vancomycin-resistant Enterococcus faecium outbreak in a nephrology ward].

L F van der Steen1, M J Bonten, E van Kregten

  • 1Universitair Medisch Centrum Utrecht, divisie Interne Geneeskunde, afd. Infectieziekten & Aids, Heidelberglaan 100, 3584 CX Utrecht.

Nederlands Tijdschrift Voor Geneeskunde
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

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An outbreak of vancomycin-resistant Enterococcus faecium (VRE) in a Dutch hospital was controlled using infection control measures. Key risk factors for VRE colonization included prior antibiotic use and hospital admission.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Hospital Epidemiology

Context:

  • An outbreak of vancomycin-resistant Enterococcus faecium (VRE) occurred in a hospital ward in April 2000.
  • VRE poses a significant challenge due to its resistance to multiple antibiotics.
  • The Eemland Hospital in the Netherlands experienced this VRE outbreak in an internal medicine/nephrology and dialysis ward.

Purpose:

  • To investigate and control an outbreak of vancomycin-resistant Enterococcus faecium (VRE).
  • To identify transmission routes and risk factors associated with VRE colonization.
  • To implement and assess the effectiveness of infection control interventions.

Summary:

  • Surveillance cultures identified 12 patients colonized with the outbreak VRE strain.

Related Experiment Videos

  • Molecular genotyping was used to analyze strain clustering.
  • Effective control measures included ward closure, patient cohorting, disinfection, strict infection control practices, and reduced vancomycin/cephalosporin prescriptions.

    • Impact:

    • The implemented infection control measures successfully controlled the VRE outbreak.
    • Identified risk factors for VRE colonization: earlier admission and previous use of ciprofloxacin, amoxicillin, and amoxicillin-clavulanic acid.
    • Highlighted the potential for inter-hospital transmission, with a nearby hospital identified as a possible source.