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Prevalence of new coronary risk factors in Thai population
C Chotinaiwattarakul1, N Mahanonda, K Bhuripanyo
1Her Majesty Cardiac Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Insights
This study investigated novel cardiovascular biomarkers for atherosclerosis in healthy Thais. High prevalence of hyperhomocysteinemia, Lp(a), and chlamydial infections were observed, highlighting potential risk factors.
Area of Science:
- Cardiovascular Medicine
- Epidemiology
- Biomarkers
Background:
- Emerging cardiovascular biomarkers for atherosclerosis lack data in the Thai population.
- Understanding these new risk factors is crucial for public health in Thailand.
Purpose of the Study:
- To determine the prevalence of novel atherosclerosis biomarkers in the healthy Thai population.
- To examine the relationship between these new risk factors and conventional atherosclerosis risk factors.
Main Methods:
- A cross-sectional survey of 3,615 healthy Thai individuals was conducted.
- Data collected included conventional risk factors and new cardiovascular biomarkers for atherosclerosis.
- Prevalence of hyperhomocysteinemia, Lp(a), and chlamydial infections were assessed.
Main Results:
- Prevalence of hyperhomocysteinemia was 27% and high Lp(a) was 32%.
- Recent chlamydial infection prevalence was 30%, and past infection was 51%.
- The study identified significant prevalence of these biomarkers in the Thai population.
Conclusions:
- Novel biomarkers like hyperhomocysteinemia and Lp(a) are prevalent in the healthy Thai population.
- Chlamydial infections are also common, suggesting a potential role in atherosclerosis.
- Further research is needed to clarify the association between these factors and atherosclerosis in Thailand.
Abstract:
Many new cardiovascular biomarkers of atherosclerosis have recently been emerging. However, there is a paucity of these data in the Thai population. This study aims to determine the prevalence of these biomarkers of atherosclerosis and the relationship between these new risk factors and other conventional risk factors for atherosclerosis in the healthy Thai population. As a yearly check-up program, we surveyed 3,615 normal healthy populations for their conventional risk factors and some new cardiovascular biomarkers for atherosclerosis. The authors found hyperhomocysteinemia and high level of Lp(a) in 27 per cent and 32 per cent of the cases respectively. Prevalence of recent and past chlamydial infection was found in 30 per cent and 51 per cent respectively.