Causes of late mortality in patients with disabling intermittent claudication

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M Kobayashi1, S Shindo, K Kubota

  • 1Second Department of Surgery, Yamanashi Medical University, Japan. masak@res.yamanashi-med.ac.jp

Japanese Circulation Journal
|February 24, 2001
PubMed

Insights

Patients with intermittent claudication face a poorer long-term prognosis. Key causes of late death include ischemic heart disease, malignancy, and cerebrovascular accidents, necessitating age-specific care strategies.

Area of Science:

  • Vascular Medicine
  • Cardiovascular Epidemiology
  • Oncology

Background:

  • Intermittent claudication (IC) is associated with a worse long-term prognosis compared to the general population.
  • Understanding the causes of late mortality in IC patients is crucial for improving outcomes.

Purpose of the Study:

  • To retrospectively review the outcomes of hospitalized patients with intermittent claudication.
  • To identify the primary causes of late death in this patient cohort.

Main Methods:

  • Retrospective review of patient records for individuals admitted with intermittent claudication.
  • Analysis of cumulative survival rates at various time points (1, 3, 5, and 10 years).
  • Categorization and comparison of major causes of death.

Main Results:

  • Cumulative survival rates at 1, 3, 5, and 10 years were 94.6%, 79.4%, 67.3%, and 37.4%, respectively.
  • Ischemic heart disease, malignancy, and cerebrovascular accident were equally prevalent causes of late death.
  • Younger patients were more likely to die from ischemic heart disease, while older patients succumbed to cerebrovascular accidents; malignancies affected all age groups similarly.

Conclusions:

  • Intermittent claudication patients exhibit significantly reduced long-term survival.
  • Age-specific mortality patterns highlight the need for tailored management strategies.
  • Targeted interventions addressing ischemic heart disease, malignancies, and cerebrovascular events are essential for this population.

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