Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Pap smear: take two.

J J Shulman, A Hontz, A Sedlis

    American Journal of Obstetrics and Gynecology
    |April 15, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study.

    Gynecologic oncology·1999
    Same author

    Prevalence, risk factors, and accuracy of cytologic screening for cervical intraepithelial neoplasia in women with the human immunodeficiency virus.

    Gynecologic oncology·1998
    Same author

    Endometriosis with massive ascites.

    Gynecologic oncology·1998
    Same author

    Papillary serous and clear cell type lead to poor prognosis of endometrial carcinoma in black women.

    Gynecologic oncology·1997
    Same author

    Vaginal intraepithelial neoplasia: risk factors for persistence, recurrence, and invasion and its management.

    American journal of obstetrics and gynecology·1997
    Same author

    Multiple recurrences of cervical intraepithelial neoplasia in women with the human immunodeficiency virus.

    Obstetrics and gynecology·1996
    Same journal

    Trends in Infertility Treatments by Race, Ethnicity, Socioeconomic Status, and Region in U.S. Birth Certificates from Live Births: 2011-2022.

    American journal of obstetrics and gynecology·2026
    Same journal

    Likelihood ratios enhance clinical interpretation of metagenomic prediction of early-onset neonatal sepsis in preterm premature rupture of membranes (Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Taking risk stratification in preterm premature rupture of membranes to the bedside (Reply to Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Gestational Age at Full-Term Delivery and Long-Term Offspring Morbidity in Low-Risk Pregnancies: A Population-Based Cohort Study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Trajectories of childbirth-related posttraumatic stress symptoms after a vaginal delivery: a multicenter prospective study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Early life adversity and polycystic ovary syndrome among North American pregnancy planners.

    American journal of obstetrics and gynecology·2026
    See all related articles

    Obtaining two cervical cytology smears significantly enhances detection of abnormal cells by 86%. This finding highlights the insensitivity of a single Pap smear for effective cervical cancer screening.

    Area of Science:

    • Gynecology
    • Cytopathology
    • Public Health

    Background:

    • Cervical cancer screening relies on accurate detection of abnormal cervical cytology.
    • The conventional single "pancervical" Pap smear may have limitations in sensitivity.

    Purpose of the Study:

    • To evaluate the efficacy of sequential "pancervical" Pap smears in detecting abnormal cervical cytology.
    • To compare the diagnostic yield of one versus two sequential Pap smears.

    Main Methods:

    • A national sample of 2,823 patients in a Family Planning Program underwent sequential "pancervical" Pap smears.
    • Data were analyzed to determine the increase in detection rates for abnormal cytology.

    Main Results:

    • Sequential "pancervical" Pap smears increased the detection of abnormal cervical cytology by 86% in the studied population.

    Related Experiment Videos

  • Participating groups in the national study also observed significant increases in sensitivity, though varying in degree.

    • Conclusions:

    • A single "pancervical" Pap smear is an insensitive method for detecting abnormal cervical cytology.
    • Sequential Pap smears improve case-finding and have implications for rescreening strategies.
    • Implementing dual Pap smear protocols could enhance cervical cancer early detection efforts.