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Meal Duration as a Measure of Orofacial Nociceptive Responses in Rodents
Published on: January 10, 2014
[Nociceptive system response to repetitive painful stimuli during chronic psychoemotional stress in humans]
I Ia Ashkinazi1, E A Vershinina
1I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
Abstract:
Repeated nocigenic stimuli applied to the skin evoked a hyperalgesia in healthy subjects while in patients with neurasthenia which is a natural model of a chronic psychoemotional stress, they evoked a hyperalgesia accompanied by sensitization. The differences in the nociceptive system responses show particularities in reactivity (plasticity) of a wide dynamic range of the spinal neurons under chronic psychoemotional stress that is due to disorders in supraspinal descending modulation system of plasticity in the spinal nociceptive neurons.
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