Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Late recurrence in medulloblastoma.

G A King, R H Sagerman

    The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine
    |January 1, 1975
    PubMed
    Summary

    Late medulloblastoma recurrences challenge established survival predictions. This study highlights cases exceeding typical cure intervals, emphasizing the need for long-term patient monitoring.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Transformation and release of micronized Cu used as a wood preservative in treated wood in wetland soil.

    Environmental pollution (Barking, Essex : 1987)·2021
    Same author

    Hairy roots of Brassica napus: II. Glutamine synthetase overexpression alters ammonia assimilation and the response to phosphinothricin.

    Plant cell reports·2013
    Same author

    Social participation of youths with cerebral palsy differed based on their self-perceived competence as a friend.

    Child: care, health and development·2011
    Same author

    Photofragment slice imaging studies of pyrrole and the Xe...pyrrole cluster.

    The Journal of chemical physics·2007
    Same author

    Measuring children's participation in recreation and leisure activities: construct validation of the CAPE and PAC.

    Child: care, health and development·2006
    Same author

    A qualitative investigation of changes in the belief systems of families of children with autism or Down syndrome.

    Child: care, health and development·2006

    Area of Science:

    • Pediatric Oncology
    • Neuro-oncology
    • Clinical Medicine

    Background:

    • Medulloblastoma is a common malignant brain tumor in children.
    • Collins' rule of survivorship is a guideline for predicting cure based on disease-free interval.
    • Late recurrences of medulloblastoma are uncommon but significant.

    Purpose of the Study:

    • To report and analyze cases of late medulloblastoma recurrence.
    • To evaluate the applicability of Collins' rule in predicting cure for medulloblastoma.
    • To underscore the importance of long-term surveillance in medulloblastoma survivors.

    Main Methods:

    • Case series presentation.
    • Review of patient records including diagnosis, treatment, and follow-up.
    • Analysis of disease-free intervals and comparison with Collins' rule.
    • Biopsy and radiographic assessment for recurrence confirmation.

    Main Results:

    • Three cases of late medulloblastoma recurrence are presented, occurring at 6 years, 6 years 7 months, and 7 years 4 months post-diagnosis.
    • Two of these cases violated Collins' rule of survivorship.
    • Recurrences were confirmed via biopsy in two cases and clinical/radiographic data in one case.

    Conclusions:

    • Late medulloblastoma recurrences can occur beyond established cure intervals.
    • Collins' rule may not accurately predict cure in all medulloblastoma cases.
    • Extended follow-up is crucial for detecting late recurrences in medulloblastoma patients.

    Related Experiment Videos