Related Experiment Video
Updated: Aug 11, 2026

Use of a Hanging-weight System for Isolated Renal Artery Occlusion
Published on: July 19, 2011
Renal cortical scintigraphy and diuresis renography in infants and children
1Department of Nuclear Medicine, Sydney Children's Hospital, Australia.
Insights
Pediatric renal scintigraphy, including 99mTc DMSA scans for urinary tract infections and 99mTc MAG3 renography for obstruction, aids in diagnosing kidney conditions. This review outlines standardized methods and discusses existing controversies in these common pediatric imaging studies.
Area of Science:
- Pediatric Nuclear Medicine
- Pediatric Radiology
- Pediatric Nephrology
Background:
- Renal scintigraphy is a common diagnostic tool in pediatric patients.
- It is primarily used to evaluate urinary tract infections (UTIs) and renal tract obstruction.
Purpose of the Study:
- To review the established indications and methodologies for pediatric renal scintigraphy.
- To highlight areas of consensus and ongoing controversy in the performance of these nuclear medicine studies.
Main Methods:
- Review of renal cortical scintigraphy using technetium-99m dimercaptosuccinic acid (99mTc DMSA) for UTI sequelae and acute pyelonephritis.
- Discussion of diuresis renography using 99mTc mercaptoacetyltriglycine (99mTc MAG3) for evaluating renal tract obstruction, particularly ureteropelvic junction obstruction.
Main Results:
- 99mTc DMSA scintigraphy is crucial for assessing chronic renal scars post-UTI.
- 99mTc MAG3 renography is highly effective for diagnosing and managing renal obstruction.
Conclusions:
- Standardized approaches exist for pediatric renal scintigraphy.
- Areas of debate in study performance require further clarification to optimize diagnostic accuracy and patient care.
Abstract:
Renal scintigraphy is performed frequently in infants and children. Renal cortical scintigraphy using 99mTc dimercaptosuccinic acid is predominantly performed to assess the renal sequelae of urinary tract infection. It is most commonly performed for the evaluation of chronic renal scars, although it is also undertaken in the assessment of acute pyelonephritis. Diuresis renography using 99mTc mercaptoacetyltriglycine is of great use in the evaluation of renal tract obstruction, which may occur at a variety of levels, but most commonly occurs at the ureteropelvic junction. Consensus statements have been formulated in an attempt to standardize methods of performing these investigations. However, several areas of controversy exist in the performance of these studies, and these are outlined. Radionuclide cystography and renal function estimation using clearance calculations are not covered in this article.
Related Concept Videos
Imaging Studies II: Ultrasonography
Imaging Studies III: Computed Tomography
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VII: Vascular Imaging
Acute Kidney Injury IV: Diagnostic Studies and Prevention

