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Immunohistochemical nuclear staining for P53 in nodular scabies
M M Mohammad1, M M Ali, H M Aidarous
1Department of Parasitology, Dermatology and Venereology and Pathology, Faculty of Medicine for Girls, Al-Azhar University, Nasr City, Cairo, Egypt.
Journal of the Egyptian Society of Parasitology
|February 24, 2001
Abstract:
Fifty patients with scabies were included in this study. Clinical, parasitological and histopathological study of all patients was done. P-53 expression was examined, using immunohistochemical techniques. Biopsies of nodular scabies showed atypical changes in the epidermis, the dermis showed dense inflammatory infiltrate. Focal positivity for P-53 have been demonstrated which could favour premalignant changes, and recommend further investigations.