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Sex differences in the renal transforming growth factor-beta 1 system after puberty

P H Lane1, D M Snelling, N Babushkina-Patz

  • 1Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska, USA. phlane@unmc.edu

Pediatric Nephrology (Berlin, Germany)
|February 24, 2001
PubMed
Summary

Transforming growth factor-beta 1 (TGF-beta 1) levels change with age and sex in rats. Male rats show more efficient TGF-beta 1 activation after puberty, potentially explaining sex differences in kidney disease.

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