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A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
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A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

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Cytoreductive surgery and adjuvant immunotherapy: a new management paradigm for metastatic melanoma

D L Morton1, D W Ollila, E C Hsueh

  • 1John Wayne Cancer Institute (JWCI), Saint John's Health Center, Santa Monica, CA, USA.

CA: a Cancer Journal for Clinicians
|February 24, 2001
PubMed

Although patients with metastatic disease are usually not offered surgery as part of their comprehensive treatment plan, the authors suggest that surgical reduction of the tumor burden may enhance the host immune response and create a favorable setting for the use of active specific immunotherapy.

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