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Optimized veno-venous bypass with the affinity pump.

C Jaggy1, M Lachat, D Inderbitzin

  • 1Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|February 24, 2001
PubMed
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The Affinity pump prevents air embolism and vessel damage during veno-venous bypass (VVBP). This new pump technology ensures stable hemodynamics with minimal intervention, making it ideal for VVBP procedures.

Area of Science:

  • Cardiovascular Surgery
  • Medical Device Technology
  • Hemodynamics

Background:

  • Veno-venous bypass (VVBP) is crucial for managing hemodynamics during procedures like hepatic vascular exclusion.
  • Existing roller and centrifugal pumps pose risks such as air embolism and endothelial damage due to negative inflow pressure.
  • These complications necessitate safer alternatives for VVBP.

Purpose of the Study:

  • To evaluate the safety and efficacy of the Affinity pump for veno-venous bypass.
  • To assess the Affinity pump's ability to prevent negative inflow pressure and associated complications.
  • To determine the hemodynamic stability maintained by the Affinity pump during VVBP.

Main Methods:

  • The Affinity pump was tested in three pigs undergoing hepatic vascular exclusion for VVBP.

Related Experiment Videos

  • Perfusion was maintained for 6 hours, with blood pumped from femoral and portal veins to the external jugular vein.
  • Hemodynamic parameters including heart rate and pressures were continuously monitored.

    • Main Results:

    • The Affinity pump successfully prevented negative inflow pressure, eliminating suction on the vessel wall and detecting no air emboli.
    • Mean pump flow was maintained at 1,629.3 +/- 372.2 ml/min throughout the 6-hour procedure.
    • Stable hemodynamics were observed, with significant decreases in mean arterial pressure and increases in femoral vein pressure post-clamping, while jugular vein pressure remained stable.

    Conclusions:

    • The Affinity pump effectively eliminates device-related complications associated with negative inflow pressure in VVBP.
    • The device ensures stable hemodynamics and requires minimal operator intervention, proving safe and simple to use.
    • The Affinity pump is highly suitable for veno-venous bypass applications.