Related Experiment Video
Updated: Oct 9, 2026
07:04
Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Evaluation of cell culture cytotoxicity of five root canal sealers
R T Leonardo1, A Consolaro, I Z Carlos
1Department of Restorative Dentistry, Faculty of Dentistry of Araraquara, UNESP, Araraquara, Brazil.
Journal of Endodontics
|February 24, 2001
Abstract:
The cytotoxicity of four calcium hydroxide-based root canal sealers (Sealapex, CRCS, Apexit, and Sealer 26) and one zinc oxide-eugenol-based sealer (Fill Canal) was evaluated microscopically for morphological changes in rat peritoneal macrophages. The least cytotoxic sealer was Fill Canal, followed in increasing order of cytotoxicity by CRCS, Sealer 26, Apexit, and Sealapex.