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Allergic Reactions

Allergic Reactions

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Allergic Reactions: Anaphylaxis

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: Jun 25, 2026

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

[Asthma caused by allergy to cat fur].

K L May¹, T Hofman

¹Instytut Gruźlicy i Chorób Płuc w Warszawie.

Przeglad Lekarski

|February 24, 2001

Summary

This summary is machine-generated.

Cat allergen Fel. d. 1 is a major cause of asthma. This review covers its environmental presence, characteristics, and elimination strategies, supported by case studies.

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Last Updated: Jun 25, 2026

Murine Model of Allergen Induced Asthma

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Published on: May 14, 2012

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

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Published on: November 1, 2014

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Published on: August 25, 2020

Area of Science:

Allergology
Environmental Health

Background:

Cat allergen Fel. d. 1 is the second leading cause of perennial atopic asthma.
Understanding Fel. d. 1 is crucial for managing allergic respiratory diseases.

Purpose of the Study:

To review the literature on Fel. d. 1 concentrations in various environments.
To discuss the structure, production, cross-reactivity, and elimination of Fel. d. 1.
To present case observations on cat-induced asthma and dermatitis.

Main Methods:

Literature review of studies on Fel. d. 1.
Analysis of environmental concentrations.
Discussion of allergen characteristics and control methods.
Retrospective case study of 20 patients.

Main Results:

Fel. d. 1 is prevalent in homes and public spaces.
Patients often do not suspect cats as an allergen source.
Cat sensitivity frequently co-occurs with other inhalant or food allergies.

Conclusions:

Effective environmental control of Fel. d. 1 is necessary.
Increased awareness of cat allergy triggers is needed.
Comprehensive allergy testing is recommended for suspected cases.