Related Experiment Video
Updated: Jul 18, 2026

Semi-automated Biopanning of Bacterial Display Libraries for Peptide Affinity Reagent Discovery and Analysis of Resulting Isolates
Published on: December 6, 2017
Staphylococcal surface display and its applications
S Ståhl1, A Robert, E Gunneriusson
1Department of Biotechnology, Kungliga Tekniska Högskolan, Stockholm, Sweden. stefans@biochem.kth.se
Abstract:
Novel surface proteins can be introduced onto the bacterial cell surface by recombinant means. Here, we describe the development of such display systems for two food-grade bacteria, Staphylococcus carnosus and Staphylococcus xylosus, and present how such engineered bacteria can be used in different applications. A study will be described in which such staphylococci were employed as vaccine delivery vehicles to elicit protective antibody responses to respiratory syncytial virus (RSV). The use of surface-engineered staphylococci as novel microbial biocatalysts, as a new type of whole-cell diagnostic devices or for adsorption of metal ions with potential environmental or biosensor applications, will also be discussed.
Related Concept Videos
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Special Staining Techniques
Surface Appendages of Archaea
Rapid Identification of Pathogens
Staphylococcal Skin Infections
Clinical Significance of Antibiotic Resistance

