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Related Experiment Videos

Lead noise with an active-fixation defibrillation lead.

R N Gelder1, J M Galvin, C M Albert

  • 1Cardiac Arrhythmia Service, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA. rgelder@partners.org

Pacing and Clinical Electrophysiology : PACE
|February 24, 2001
PubMed
Summary

A specific implantable cardioverter defibrillator lead can cause lead artifact, leading to inappropriate detections. This unique issue often resolves within four weeks, preventing unnecessary therapies.

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Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Inappropriate detection and therapy are common adverse events in implantable cardioverter defibrillator (ICD) therapy.
  • Lead artifact, often presenting late due to lead component stress, is a known mechanism for these inappropriate events.

Observation:

  • This study describes experience with Endotak Endurance EZ leads (Models 0154/0155/0156).
  • Of 20 implants, four patients exhibited noise leading to inappropriate detections in three.
  • No patient received therapy due to these detections.

Findings:

  • The artifact appeared early post-implant and resolved in three of four affected patients by four weeks.
  • No noise developed in the remaining 16 patients after this initial period.
  • This specific lead problem is unique in its transient nature.

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Implications:

  • While resolving over time, this lead artifact can still cause inappropriate therapies and management challenges.
  • Careful monitoring is needed, especially in high-risk patients with ventricular arrhythmias.
  • Understanding lead behavior is crucial for optimizing ICD therapy safety and efficacy.