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Updated: Aug 12, 2026

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
Published on: November 12, 2019
AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
1Clinical Oncology Unit, University of Bradford, UK. r.m.phillips@bradford.ac.uk
Abstract:
The pace of anticancer drug discovery and development has accelerated over recent years based upon a better understanding of tumour biology at the molecular level. Modern drug development has moved from empiricism to rational design and this was the theme of the inaugural meeting of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics held in Washington DC, November 16 - 19.1999. This was an excellent meeting where state of the art research in the areas of drug discovery, development and clinical evaluation of new cancer therapeutics was presented. A few of the highlights of this meeting are presented in this article but further details can he found in a supplement to Clinical Cancer Research (1999) 5:3729-3897, where all abstracts accepted for the meeting are published. This meeting is set to become the premier meeting for scientists and clinicians involved in all aspects of anticancer drug development (i.e., from bench to the bedside) and the next meeting will take place in Amsterdam on November 7-10, 2000.
Insights
Advances in molecular biology accelerate anticancer drug discovery. The AACR-NCI-EORTC conference highlighted rational drug design, moving beyond empiricism for novel cancer therapeutics.
Area of Science:
- Oncology
- Molecular Biology
- Pharmacology
Background:
- Anticancer drug discovery has accelerated due to a deeper understanding of tumor biology at the molecular level.
- Modern drug development emphasizes rational design over traditional empirical methods.
Framework:
- The inaugural AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics focused on rational drug design.
- The conference showcased state-of-the-art research in drug discovery, development, and clinical evaluation of cancer therapeutics.
Implementation:
- Key research areas included molecular targets and novel therapeutic strategies.
- Presentations covered the entire spectrum of anticancer drug development, from basic research to clinical application.
Implications:
- The conference established itself as a premier event for scientists and clinicians in anticancer drug development.
- Future meetings are planned to foster continued collaboration and advancement in the field.
- The shift to rational design promises more effective and targeted cancer treatments.
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