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A comparative study of 2 fluoride-based mouthrinses
B Hagedorn1, B Willershausen, C P Ernst
1Department of Restorative Dentistry and Periodontology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany.
Quintessence International (Berlin, Germany : 1985)
|February 24, 2001
Summary
Both conventional and alcohol-free Meridol mouthrinses effectively reduce plaque and gingivitis. This study found no significant difference in effectiveness between the two Meridol formulations, making alcohol content irrelevant to their performance.
Area of Science:
- Oral hygiene and periodontology.
- Clinical dentistry and therapeutic interventions.
Background:
- Gingivitis and plaque accumulation are common oral health issues.
- Mouthrinses are often used as adjuncts to regular oral hygiene practices.
Purpose of the Study:
- To compare the clinical effectiveness of conventional Meridol mouthrinse versus an alcohol-free Meridol formulation.
- To evaluate the impact of alcohol content on mouthrinse efficacy in reducing plaque and gingivitis.
Main Methods:
- A 3-week, single-blind, controlled clinical study involving 80 healthy adult subjects.
- Subjects used either conventional or alcohol-free Meridol mouthrinse three times daily, supplementing routine oral hygiene.
- Oral health was assessed using the approximal plaque index, sulcular bleeding index, and gingival index.
Main Results:
- Both mouthrinse groups demonstrated statistically significant reductions in plaque accumulation and gingival inflammation (bleeding).
- No significant difference in efficacy was observed between the conventional and alcohol-free Meridol mouthrinses.
- Reversible tooth and tongue staining occurred in less than one-third of participants in both groups.
Conclusions:
- The alcohol content of Meridol mouthrinse does not influence its effectiveness in reducing plaque and gingivitis.
- Both conventional and alcohol-free Meridol mouthrinses are equally effective therapeutic adjuncts for improving oral hygiene.