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Mechanical circulatory support systems--a review.

D Mihaylov1, G J Verkerke, G Rakhorst

  • 1Department of BioMedical Engineering, University of Groningen, Faculty of Medical Sciences, The Netherlands. D.Mihaylov@med.rug.nl

Technology and Health Care : Official Journal of the European Society for Engineering and Medicine
|February 24, 2001
PubMed
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Mechanical Circulatory Support Systems (MCSS) offer solutions for end-stage heart failure when transplantation is not an option. Advanced devices provide improved mobility and quality of life for patients.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Congestive Heart Failure (CHF) presents a significant health challenge with high mortality.
  • Heart transplantation, the definitive treatment for CHF, faces limitations due to donor organ scarcity.
  • Mechanical Circulatory Support Systems (MCSS) have been developed to address these limitations.

Purpose of the Study:

  • To review the evolution of MCSS, including Ventricular Assist Devices (VADs) and Total Artificial Hearts (TAHs).
  • To highlight the clinical indications and contraindications for MCSS implantation.
  • To analyze the advantages, disadvantages, and outcomes of various MCSS.

Main Methods:

  • Categorization and review of MCSS development.
  • Analysis of medical indications and contraindications for pump implantation.

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  • Evaluation of results from animal and clinical studies.

    • Main Results:

    • Early MCSS relied on external pneumatic drives.
    • Modern VADs and TAHs are electrically powered, fully implantable, and portable.
    • These advancements enable patients to resume daily activities.

    Conclusions:

    • MCSS are crucial for managing end-stage heart failure and bridging patients to transplantation or providing permanent support.
    • Technological advancements have significantly improved patient mobility and quality of life.
    • Further research and development in MCSS continue to expand treatment options for CHF.