Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minimally invasive direct access heart valve surgery.

J G Byrne1, M K Hsin, D H Adams

  • 1Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115,USA. JGBYRNE@BICS.BWH.HARVARD.EDU

Journal of Cardiac Surgery
|February 24, 2001
PubMed
Summary

Minimally invasive direct access (MIDA) heart valve surgery, including aortic valve replacement and mitral valve repair/replacement, demonstrates safety and effectiveness. This approach offers favorable outcomes for patients needing elective aortic or mitral valve procedures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Update on: a meta-analysis of sperm donation offspring health outcomes - 2018 update.

Journal of developmental origins of health and disease·2018
Same author

Low-dose interleukin-2 promotes STAT-5 phosphorylation, T<sub>reg</sub> survival and CTLA-4-dependent function in autoimmune liver diseases.

Clinical and experimental immunology·2017
Same author

A meta-analysis of sperm donation offspring health outcomes.

Journal of developmental origins of health and disease·2016
Same author

A meta-analysis of neonatal health outcomes from oocyte donation.

Journal of developmental origins of health and disease·2015
Same author

Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy.

The British journal of dermatology·2015
Same author

Pediatric Liver Transplant Recipients Who Undergo Transfer to the Adult Healthcare Service Have Good Long-Term Outcomes.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015

Area of Science:

  • Cardiovascular Surgery
  • Minimally Invasive Cardiac Surgery
  • Heart Valve Repair and Replacement

Background:

  • Minimally invasive direct access (MIDA) surgery is an evolving technique for cardiac procedures.
  • Evaluating the safety and efficacy of MIDA for aortic and mitral valve operations is crucial for clinical practice.
  • Previous studies have explored various minimally invasive approaches, necessitating a review of MIDA's specific outcomes.

Purpose of the Study:

  • To review the institutional experience with MIDA heart valve surgery.
  • To assess the perioperative and late outcomes of MIDA aortic valve replacement/repair and mitral valve repair/replacement.
  • To determine the overall safety and effectiveness of MIDA for isolated elective aortic or mitral valve surgery.

Main Methods:

Related Experiment Videos

  • Retrospective review of 518 patients undergoing MIDA heart valve surgery.
  • Data collection included patient demographics, surgical approach, perioperative complications, and follow-up outcomes.
  • Analysis of outcomes for two cohorts: MIDA aortic valve replacement/repair (252 patients) and MIDA mitral valve repair/replacement (266 patients).

    • Main Results:

    • For MIDA aortic valve surgery (250 AVRs): 2% operative mortality, low rates of perioperative complications (e.g., bleeding, infection, stroke), and favorable long-term outcomes with low reoperation and late death rates.
    • For MIDA mitral valve surgery (266 cases): 0.8% operative mortality, low perioperative complication rates (e.g., bleeding, stroke, infection), and good long-term results with minimal reoperations and late deaths.
    • Significant improvement in New York Heart Association (NYHA) functional class post-operatively for both aortic and mitral MIDA procedures.

    Conclusions:

    • Minimally invasive direct access (MIDA) heart valve surgery is a safe and effective option for selected patients.
    • The MIDA approach yields low operative mortality and morbidity for both aortic and mitral valve interventions.
    • MIDA surgery leads to significant functional improvement, supporting its role in elective isolated aortic or mitral valve surgery.