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Updated: Jul 15, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Cleft lip and palate care in the United Kingdom--the Clinical Standards Advisory Group (CSAG) Study. Part 3: speech
D Sell1, P Grunwell, S Mildinhall
1Department of Speech and Language Therapy at the Great Ormond Street Hospital for Children, London, England. debbie.sell@gosh-tr.nthames.nhs.uk
Objective:
To summarize speech outcomes in children born with unilateral cleft lip and palate (UCLP) throughout the United Kingdom.
Design:
Prospective descriptive study on a cross-sectional sample of children.
Patients/Participants:
Data were collected for 238 5-year-olds (born between April 1, 1989, and March 31, 1991) and 218 12-year-olds (born between April 1, 1982, and March 31, 1984) with complete UCLP.
Main Outcomes:
Ratings of intelligibility, nasality, "speech cleft type characteristics" and speech therapy intervention.
Conclusions:
Nineteen percent of 5-year-olds and 4% of 12-year-olds were judged to be impossible to understand or just intelligible to strangers. Thirty-four percent of 5-year-olds and 17% of 12-year-olds had at least one serious error of consonant production. Eighteen percent of 5-year-olds and 12-year-olds had consistent hypernasality of mild, moderate, or severe degree. Approximately two-thirds of both age groups had undergone speech therapy.
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