Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cellular signaling in tissue regeneration.

W J Kim1

  • 1Department of Medicine, Mount Sinai School of Medicine of New York University, NY 10029, USA. william.kim@mountsinai.org

Yonsei Medical Journal
|February 24, 2001
PubMed
Summary

Stem cell research shows growth factors are key to tissue regeneration and wound healing. Understanding their signaling pathways can lead to better therapies for tissue repair.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early Versus Delayed Treatment for Gartland Type III Supracondylar Humeral Fractures in Children: A Systematic Review and Meta-analysis.

Indian journal of orthopaedics·2022
Same author

Nicotinamide Improves Delayed Tooth Eruption in <i>Runx2</i><sup></sup> Mice.

Journal of dental research·2020
Same author

Delay-adjusted age- and sex-specific case fatality rates for COVID-19 in South Korea: Evolution in the estimated risk of mortality throughout the epidemic.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2020
Same author

Distinctive patterns of pulmonary function change according to baseline lung volume and diffusing capacity.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2020
Same author

Comparison of Hot Deformation Behavior Characteristics Between As-Cast and Extruded Al-Zn-Mg-Cu (7075) Aluminum Alloys with a Similar Grain Size.

Materials (Basel, Switzerland)·2019
Same author

PIN1 is a new therapeutic target of craniosynostosis.

Human molecular genetics·2018

Area of Science:

  • Stem cell biology
  • Molecular signaling
  • Regenerative medicine

Background:

  • Stem cell research has advanced tissue regeneration significantly.
  • Growth factors and cytokines are crucial for stem cell differentiation and tissue repair.
  • The precise mechanisms of growth factor signaling in regeneration are not fully understood.

Purpose of the Study:

  • To review the potential underlying mechanisms of growth factor signaling in tissue regeneration.
  • To discuss the role of growth factors in normal tissue repair and chronic wound healing.
  • To provide a foundation for developing targeted regenerative therapies.

Main Methods:

  • Literature review focusing on growth factor signaling pathways.
  • Analysis of receptor kinases and G protein-coupled receptors in tissue regeneration.
  • Synthesis of current understanding of molecular mechanisms in regeneration.

Main Results:

  • Growth factors and cytokines play a vital role in stem cell differentiation.
  • Signal transduction pathways involving receptor kinases and G protein-coupled receptors are central to regeneration.
  • Understanding these pathways is crucial for effective wound healing and tissue repair.

Conclusions:

  • Growth factor signaling is fundamental to tissue regeneration and wound healing.
  • Further research into these mechanisms will enable the design of advanced regenerative therapies.
  • This review consolidates current knowledge to guide future therapeutic strategies.

Related Experiment Videos