Hydraphile channels: models for transmembrane, cation-conducting transporters
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Updated: Oct 9, 2026
07:47
A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
Published on: April 20, 2015
1Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63110, USA. ggokel@molecool.wustl.edu
Chemistry (Weinheim an Der Bergstrasse, Germany)
|February 24, 2001
Abstract:
A completely synthetic, non-peptide channel has been prepared and shown to conduct cations across a phospholipid bilayer membrane. Studies have been undertaken to assess the compound's location within the bilayer and to better understand its function. These studies are described along with background on the design and concept of the channel.
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