Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early onset multiple sclerosis.

I L Simone1, D Carrara, C Tortorella

  • 1Department of Neurological and Psychiatric Sciences, University of Bari, Italy.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|February 24, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Colorectal cancer patients-derived immunity-organoid platform unveils cancer-specific tissue markers associated with immunotherapy resistance.

Cell death & disease·2024
Same author

Emergence of Mycobacterium gordonae in heater-cooler units: a five-year prospective surveillance of devices frequently subjected to chloramine-T booster disinfection.

The Journal of hospital infection·2024
Same author

Clinical Profiles and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis: A Cluster-Based Approach Based on MR Imaging Metrics.

AJNR. American journal of neuroradiology·2023
Same author

Do patients' and referral centers' characteristics influence multiple sclerosis phenotypes? Results from the Italian multiple sclerosis and related disorders register.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2022
Same author

A multicenter survey on access to care in Multiple Sclerosis-related trigeminal neuralgia.

Journal of the neurological sciences·2021
Same author

A 71-nucleotide deletion in the periaxin gene in an Italian patient with late-onset slowly progressive demyelinating Charcot-Marie-Tooth disease.

European journal of neurology·2020
Same journal

Brain-muscle axis regulation of neuroinflammation and sarcopenia in Parkinson's disease: the bridging role of lactylation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Early and severe masticatory muscle involvement in SOD1-ALS: a case report with biomarker-clinical dissociation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Early multimodal predictors of good neurological outcome in comatose patients after cardiac arrest: a prospective single-center cohort study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Telemedicine for headache disorders in real-world practice: from patient experience to health system impact.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Topography and functional connectivity analysis of heart surgery-associated brain lesions: a literature review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Limb apraxia in Parkinson's disease and atypical parkinsonian syndromes: a systematic review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
See all related articles

Early onset multiple sclerosis (MS) typically affects women and often begins with vision loss. While generally having a good prognosis with slow progression, some cases show poor outcomes linked to relapse frequency and delayed treatment.

Area of Science:

  • Neurology
  • Immunology
  • Clinical Medicine

Background:

  • Multiple sclerosis (MS) typically manifests in adults aged 20-40.
  • Early onset MS (EOMS) frequency varies (2.7%-5%), with a higher prevalence in females post-puberty.
  • Visual disturbances are common initial symptoms in EOMS.

Purpose of the Study:

  • To summarize the clinical characteristics and prognostic factors of early onset multiple sclerosis (EOMS).
  • To review the typical disease course and recovery patterns observed in EOMS patients.

Main Methods:

  • Literature review of studies reporting on early onset multiple sclerosis.
  • Analysis of reported frequencies, initial symptoms, disease course, and prognostic indicators in EOMS.

Related Experiment Videos

Main Results:

  • EOMS predominantly affects females and often presents with visual loss.
  • The disease typically follows a relapsing-remitting course with good initial recovery.
  • A slow progression rate and long intervals between attacks are characteristic of EOMS.

Conclusions:

  • EOMS generally has a favorable prognosis with slow progression and good recovery.
  • Poor outcomes in a subset of EOMS cases are associated with frequent relapses and delayed treatment intervals.