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Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
Published on: October 3, 2025
Missed abortion complicated by Candida infection in a woman with rested IUD
L C Horn1, P Nenoff, M Ziegert
1Institute of Pathology, Gynaecopathology, University of Leipzig, Germany. hornl.@medizin.uni-leipzig.de
Abstract:
Although Candida species are frequent saprophytes of the female genital tract, chorioamnionitis or intrauterine fetal infections are rarely caused by these fungi. The present report describes a 34-year-old woman G2, P2, presenting with vaginal bleeding in the 11.6 weeks of gestation. Clinical and sonographic examination revealed a missed abortion and rested IUD. Histopathologically, a fungal chorioamnionitis due to Candida spp. was found at the curetting material, confirmed by detection of C. albicans infection on mycological culture. Foreign intrauterine bodies, like IUD's and cerclage sutures predispose to fungal chorioamnitis or fetal infections. This conditions urge repetetive search for Candida spp. to establish early anti-fungal therapy which may be therapeutic for this hithero rare intrauterine infection.
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