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Synthesis and evaluation of caffeic acid amides as antioxidants
P Rajan1, I Vedernikova, P Cos
1Department of Medicinal Chemistry, University of Antwerpen (UIA), Belgium.
Bioorganic & Medicinal Chemistry Letters
|February 24, 2001
Abstract:
A series of amides of caffeic acid has been synthesised and their antioxidant properties evaluated as lipid peroxidation inhibitors. Anilides of caffeic acid were found to be very efficient antioxidants with IC50's of 0.3 microM.