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Comparison of cervical smears secured with different instruments
P Valenzuela1, P Martinez, A Santana
1Department of Obstetrics and Gynecology, Hospital Universitario Principe de Asturias, Madrid, Spain.
Acta Obstetricia Et Gynecologica Scandinavica
|February 24, 2001
Summary
The combination of cervical brush and Ayre
Area of Science:
- Gynecologic Cytology
- Cervical Cancer Screening
Background:
- Comparison of sample collection devices for cervical cytology.
- Evaluation of cervical brush and Ayre's wooden spatula versus Acellon Combi.
Purpose of the Study:
- To compare the efficacy of cervical brush and Ayre's wooden spatula against Acellon Combi for cervical smear sample collection.
- To assess the quantity and preservation of cellular material obtained by different sampling methods.
Main Methods:
- Cross-sectional study involving 1000 cervical smears.
- Randomized use of cervical brush for endocervix and Ayre's wooden spatula for exocervix, or Acellon Combi for both sampling areas.
Main Results:
- Cervical brush/spatula combination yielded acceptable columnar cells in 71.6% vs. 61.7% for Acellon Combi (p<0.01).
- Brush/spatula yielded acceptable squamous cells in 87.5% vs. 77.4% for Acellon Combi (p<0.001).
- Significantly better cellular preservation in endocervical samples with brush technique compared to Acellon Combi.
Conclusions:
- Cervical brush and Ayre's wooden spatula provide superior quantity and preservation of cells for cervical smears.
- The combination of brush and spatula is recommended over Acellon Combi for improved cervical cytology sample quality.