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Adverse granulomatous reaction after cosmetic dermal silicone injection
1Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
Background:
Various alloplastic injectable implants have been developed for soft tissue augmentation without surgery, but different local or systemic adverse reactions have limited their use for cosmetic purposes.
Objective:
To examine the problems associated with silicone injection.
Methods:
Case report and literature review.
Results:
We describe an adverse granulomatous reaction after the injection of liquid silicone for lip augmentation, causing facial disfigurement. Although the initial response to steroids was poor, after 3 years of follow-up the nodules have almost disappeared spontaneously.
Conclusion:
We advise that silicone injection be performed solely by trained physicians using medical-grade silicone or consider other injectable materials.