Quantitative characterization of hemodialyzer solute and water transport

Clinicians are frequently faced with the task of selecting a hemodialyzer for a dialysis-dependent patient. Several quantitative dialyzer parameters, such as clearance, sieving coefficients, and ultrafiltration coefficient, are routinely used in this selection process. However, the quantitative basis and exact meaning of these indices are often unclear or misinterpreted. The purpose of this article is to provide a detailed description of several of these parameters with the hope that this information will enable clinicians to make dialyzer selection from a more quantitative perspective.