Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic pyelonephritis. Electron microscopic study. III. The ureter.

E N Fussell, J A Roberts

    Investigative Urology
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Association of intra-operative metaphyseal fractures with prosthesis size during hemiarthroplasty of the hip.

    Journal of orthopaedic surgery (Hong Kong)·2008
    Same author

    Automated characterization of multiple alpha peaks in multi-site electroencephalograms.

    Journal of neuroscience methods·2007
    Same author

    Ozone affects gas exchange, growth and reproductive development in Brassica campestris (Wisconsin fast plants).

    The New phytologist·2007
    Same author

    Distribution of Metacercariae of Fasciola gigantica on rice straw.

    Tropical animal health and production·2007
    Same author

    The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection.

    The Journal of antimicrobial chemotherapy·2007
    Same author

    The effect of temperature and humidity on longevity of metacercariae of Fasciola gigantica.

    Tropical animal health and production·2006

    Chronic pyelonephritis causes significant ultrastructural damage to the nonhuman primate ureter. These changes, including epithelial damage and leukocyte invasion, appear reparative and resemble ureteral obstruction effects.

    Area of Science:

    • Urology
    • Pathology
    • Comparative Anatomy

    Background:

    • The ureter's ultrastructure is crucial for urinary tract function.
    • Chronic pyelonephritis can lead to significant renal and ureteral pathology.
    • Understanding ureteral changes in nonhuman primates provides insights into human conditions.

    Purpose of the Study:

    • To describe the ultrastructural changes in the ureter of nonhuman primates with experimentally induced chronic pyelonephritis.
    • To compare these changes with those observed in ureteral obstruction.

    Main Methods:

    • Transmission electron microscopy was used to examine ureteral tissue.
    • Experimental chronic pyelonephritis was induced in nonhuman primates.
    • Histological analysis focused on epithelial, connective tissue, and smooth muscle layers.

    Related Experiment Videos

    Main Results:

    • Extensive ultrastructural damage was observed throughout the ureter wall.
    • Epithelial cells showed progressive damage from basal to superficial layers.
    • Leukocyte invasion occurred in intercellular spaces; connective tissue thickened with increased fibroblasts, collagen, and elastic fibers.
    • Smooth muscle layers exhibited damage and altered interdigitating nexuses.

    Conclusions:

    • Experimentally induced chronic pyelonephritis causes severe ultrastructural alterations in the nonhuman primate ureter.
    • The observed changes share similarities with those seen in ureteral obstruction.
    • These ureteral modifications are hypothesized to be part of a reparative process.