Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alcohol and the developing fetus--a review.

J D Chaudhuri1

  • 1Department of Anatomy, Faculty of Medicine, University Malaya, 50603 Kuala Lumpur, Malaysia. joydeep@medicine.med.um.edu.my

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|February 24, 2001
PubMed
Summary

Fetal alcohol syndrome (FAS) presents with varied physical and mental effects in children due to prenatal alcohol exposure. This review details FAS clinical features, experimental findings, and prevention strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical education: time for a change.

Journal of the Indian Medical Association·2010
Same author

Preconception counseling in the prevention of fetal alcohol syndrome: a unique window of opportunity.

La Clinica terapeutica·2009
Same author

Anatomico-radiological study of asymmetrical articular facets on occipital condyles and its clinical implications.

Kathmandu University medical journal (KUMJ)·2008
Same author

Outcome of coronary bypass grafting.

Indian journal of medical sciences·2007
Same author

The need for personality development among medical students.

Journal of the Indian Medical Association·2005
Same author

Localization of M2 muscarinic receptor protein in parvalbumin and calretinin containing cells of the adult rat entorhinal cortex using two complementary methods.

Neuroscience·2005

Area of Science:

  • Teratology
  • Developmental Biology
  • Pediatrics

Background:

  • Fetal alcohol syndrome (FAS) is a spectrum of developmental disorders caused by prenatal alcohol exposure.
  • Clinical manifestations of FAS exhibit significant variability, impacting physical, cognitive, and behavioral development.
  • Understanding FAS is crucial due to its increasing incidence and lifelong consequences.

Purpose of the Study:

  • To comprehensively describe the diverse clinical features of Fetal Alcohol Syndrome.
  • To review experimental findings from animal models and correlate them with human FAS cases.
  • To discuss potential mechanisms of alcohol-induced teratogenicity and suggest preventive measures.

Main Methods:

  • Literature review of clinical observations in humans.

Related Experiment Videos

  • Analysis of data from animal and avian experimental models studying alcohol's effects on development.
  • Discussion of proposed teratogenic mechanisms and prevention strategies.

    • Main Results:

    • FAS is characterized by a range of physical anomalies, including craniofacial dysmorphies and growth deficits.
    • Cognitive impairments, such as intellectual disability and behavioral problems, are common.
    • Experimental models demonstrate alcohol's teratogenic potential, with findings correlating to human FAS presentations.

    Conclusions:

    • Fetal alcohol syndrome encompasses a wide spectrum of developmental abnormalities.
    • Animal models provide valuable insights into FAS pathogenesis, despite ethical limitations in human studies.
    • Prevention through maternal alcohol abstinence during pregnancy is paramount.