Related Experiment Video

Updated: Oct 9, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

[Emerging mycoses]

G Piédrola Angulo

    Anales De La Real Academia Nacional De Medicina
    |February 24, 2001
    PubMed

    Insights

    The incidence of pathogenic fungi is increasing due to factors like aging populations and hospital practices. This study reviews emerging fungal infections, their clinical signs, and treatment strategies.

    Area of Science:

    • Medical Mycology
    • Infectious Diseases
    • Clinical Microbiology

    Background:

    • Rising incidence of pathogenic fungal agents, particularly in vulnerable patient groups (elderly, immunocompromised).
    • Contributing factors include increased hospital instrumentation and widespread use of antibiotics and antimycotics.
    • Focus on emerging filamentous, dimorphic fungi, and yeasts causing infections.

    Discussion:

    • Clinical manifestations associated with emerging fungal pathogens.
    • Diagnostic approaches for identifying these fungi.
    • Therapeutic strategies for treating fungal infections.

    Key Insights:

    • Identification of key emerging fungal pathogens in clinical settings.
    • Correlation between patient risk factors and fungal infection development.
    • Overview of current diagnostic and treatment protocols for fungal diseases.

    Outlook:

    • Need for continued surveillance of emerging fungal infections.
    • Importance of rational antimicrobial and antimycotic use.
    • Potential for novel diagnostic and therapeutic advancements in medical mycology.

    More Related Videos

    An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract07:42

    An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

    Published on: July 1, 2020

    Related Concept Videos

    Skin Diseases and Disorders01:23

    Skin Diseases and Disorders

    Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
    Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
    Cryptococcal Meningitis01:27

    Cryptococcal Meningitis

    Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
    Antifungal Agents01:15

    Antifungal Agents

    Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...
    Fungal Phylum Microsporidia01:28

    Fungal Phylum Microsporidia

    Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
    Candidiasis01:20

    Candidiasis

    Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
    Fungal Phylum Ascomycota01:28

    Fungal Phylum Ascomycota

    Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...