Related Experiment Video
Updated: Oct 9, 2026

Live-cell Imaging of Fungal Cells to Investigate Modes of Entry and Subcellular Localization of Antifungal Plant Defensins
Published on: December 24, 2017
Nematicidal alkaloids and related compounds produced by the fungus Penicillium cf. simplicissimum
1Department of Agricultural Chemistry, Faculty of Agriculture, Tottori University, Japan.
Abstract:
A new nematicidal alkaloid, peniprequinolone (1), together with the known alkaloids penigequinolones A and B (2a, 2b), 3-methoxy-4-hydroxy-4-(4'-methoxyphenyl)quinolinone (3), and 3-methoxy-4,6-dihydroxy-4-(4'-methoxyphenyl)quinolinone (4), were isolated from Penicillium cf. simplicissimum (Oudemans) Thom. Cyclopenin (5) and a compound (6a/6b) structurally related to cyclopenin also were isolated from the fungus, and their structures were established by spectroscopic analysis. The biological activities of 1, 2, 3, 4, and 5 were examined by a bioassay with root-lesion nematodes.
Related Concept Videos
Antifungal Agents
Anthelminthic Agents
Fungal Phylum Ascomycota
Production of Antibiotics
Fungal Phylum Basidiomycota
Physical Properties of Amines

