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Published on: April 14, 2023
Stability and bioavailability of antioxidants in garland (Chrysanthemum coronarium L.)
M Takenaka1, T Nagata, M Yoshida
1National Food Research Institute, Ministry of Agriculture, Forestry, and Fisheries, Tsukuba, Ibaraki, Japan. tknk1221@nfri.affrc.go.jp
Abstract:
The stability and bioavailability of the major antioxidants in garland (Chrysanthemum coronarium L.), chlorogenic acid, 3,5-dicaffeoylquinic acid and 4-succinyl-3,5-dicaffeoylquinic acid, were investigated together with caffeic acid. These compounds were stable in artificial digestive juice, but more than 90% of them disappeared from plasma within 30 min after intravenous injection into rats. When they were orally administered, only caffeic acid could be detected.

