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Related Experiment Videos

Brain surface ependymoma.

Y Sato1, H Ochiai, Y Yamakawa

  • 1Department of Pathology, Prefectural Hospital Miyazaki, Miyazaki Medical College, Japan. ysugar@pref-hp.miyazaki.miyazaki.jp

Neuropathology : Official Journal of the Japanese Society of Neuropathology
|February 24, 2001
PubMed
Summary
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This report details a rare brain surface ependymoma in a 41-year-old woman. Surgical removal was successful for this supratentorial tumor, offering insights into its unique presentation and histology.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Neuropathology

Background:

  • Ependymomas are typically intraventricular tumors.
  • Brain surface ependymomas are exceptionally rare, posing diagnostic and surgical challenges.

Observation:

  • A 41-year-old woman presented with right upper limb weakness.
  • MRI revealed a left fronto-parietal cystic tumor with a calcified mural nodule.
  • The tumor was superficial, well-demarcated, and not connected to the ventricles.

Findings:

  • Histology showed ependymoma with true ependymal and perivascular pseudorosettes.
  • A clear cell component, resembling oligodendroglioma, was also present.
  • Tumor cells were positive for glial fibrillary acid protein and vimentin.

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Implications:

  • This case expands the known locations for ependymomas.
  • Highlights the importance of considering rare tumor types in differential diagnosis.
  • Successful surgical resection of superficial ependymomas is feasible.