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Chromosome aberrations in human lymphocytes after irradiation with 15.0-MeV neutrons in vitro. I. Dose-response
Mutation Research
|January 1, 1975
Abstract:
Human peripheral lymphocytes were irradiated with different doses of 15.0-MeV neutrons. The frequency of different aberration types was determined and the dose-response relation was calculated. The data were fitted by least-squares regression analysis to different models. The dicentric, dicentric plus centric ring, and different acentric data gave the best fit to the linear quadratic model. The RBE of 15.0-MeV neutrons versus 220 kV X-rays decreased significantly with increasing dose.