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Related Experiment Videos

[Sufentanyl in balanced anesthesia for neurosurgery. Comparative study with fentanyl] .

T Cafiero1, P Mastronardi

  • 1Servizio di Anestesia e Rianimazione, Ospedale San Rocco Sessa Aurunca, ASL CE/2. tulliocafiero@libero.it

Minerva Anestesiologica
|February 24, 2001
PubMed
Summary

Sufentanil provided better cardiocirculatory stability and longer postoperative analgesia compared to fentanyl during balanced anesthesia for neurosurgery. This suggests sufentanil is a viable alternative analgesic for these procedures.

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Area of Science:

  • Anesthesiology
  • Neurosurgery
  • Pharmacology

Background:

  • Balanced anesthesia is commonly used in neurosurgery.
  • Opioid analgesics like fentanyl and sufentanil are crucial for managing pain and hemodynamic stability during these procedures.

Purpose of the Study:

  • To compare the effects of sufentanil and fentanyl in patients undergoing neurosurgery under balanced anesthesia.
  • To evaluate hemodynamic stability, recovery time, and postoperative analgesia.

Main Methods:

  • A prospective randomized study involving 50 neurosurgery patients (ASA I-II).
  • Patients received either sufentanil or fentanyl as premedication and for intraoperative analgesia.
  • Hemodynamic parameters, ECG, ETCO2, pulsoximetry, recovery time, and postoperative pain (VAS) were monitored.

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Main Results:

  • Sufentanil group showed improved cardiocirculatory stability with less significant changes in Mean Arterial Pressure (MAP) and Heart Rate (HR).
  • Patients receiving sufentanil experienced shorter recovery times and more prolonged postoperative analgesia.
  • Lower inspiratory concentrations of volatile anesthetic agents were required in the sufentanil group.

Conclusions:

  • Sufentanil offers superior cardiocirculatory stability and enhanced postoperative pain relief in neurosurgical patients compared to fentanyl.
  • Sufentanil is a safe and effective alternative analgesic for balanced anesthesia in neurosurgery.